Monkeypox (MPOX) Vaccination Centre

Since May 2022 an international outbreak of monkeypox (MPOX) among gay, bisexual and other men who have sex with men (GBMSM) has been reported. Skin-to-skin contact (including sexual contact) has been the predominant mode of transmission in this outbreak. Most people experience a mild illness and recover within a few weeks.  

In response, NSW Health has worked with the Commonwealth and other jurisdictions to identify cases and and contain further spread through comprehensive surveillance and vaccination programs.  

The MPOX Vaccination Centre is located at:

Sacred Heart Health Service, Level 2 North, room 235
170 Darlinghurst Road, Darlinghurst NSW 2010

Operating Monday to Friday, 08:30am - 04:00pm

Please note: Update: We will be closed during the Christmas Holiday Period, December 24th, 2022 - January 2nd, 2023. Any bookings made during this period will be automatically moved to Tuesday January 3rd, 2023.


People eligible to receive the vaccine are gay and bisexual men (cis and trans) with multiple or casual sexual partners and anyone who has sex with these men, including women (cis and trans) and non-binary people.

If this criteria applies to you, you can book your vaccine via NSW Health Booking portal:

For booking support: Monday to Friday, 8:30am - 04:00pm only, phone (02) 8382 1111, ask the St Vincent's Switchboard to transfer you to The St Vincent’s Hospital Monkeypox Vaccination Centre.

If you are not yet eligible for the vaccine, please continue to check this page for the latest information on the vaccine rollout in NSW. We thank you for your patience.

Please call Sexual Health Info Link on 1800 451 624 for general MPOX questions.