St Vincent’s Pioneered AI-Based Solution for Monitoring Multiple Sclerosis

St Vincent’s Pioneered AI-Based Solution for Monitoring Multiple Sclerosis

13 Nov 2023

We are super-proud to have partnered with Sydney Neuroimaging Analysis Centre (SNAC) and international collaborators to demonstrate the benefits of a clinically integrated AI-based tool, iQ-Solutions, for monitoring patients with multiple sclerosis (MS).

The pioneering work has been published in a landmark study in Nature Portfolio’s npj Digital Medicine.
 
In the largest and most comprehensive clinical validation of a quantitative MRI monitoring tool for MS, the sensitivity of SNAC’s iQ-Solutions for the detection of active disease (the development of new or enlarging lesions) was 93.3%, compared to only 58.3% for standard radiology reports, in 397 multi-centre MRI scan pairs acquired in routine practice.

“MRI plays a crucial role in detecting new areas brain of brain inflammation in MS, even if they do not cause symptoms – providing clinicians with an opportunity to escalate treatment to prevent longer term disability. Our work synergises human knowledge with AI to enhance radiological monitoring of chronic diseases such as MS, leading to improved patient outcomes, said the study’s senior author, Dr Yael Barnett, St Vincent's senior staff Radiologist.

The fully-automatic tool was also able to detect and measure accelerated loss of brain tissue between scans acquired approximately 12 months apart, whereas even more severe brain atrophy (>0.8% loss over 1 year) was not appreciated in radiology reports.

 

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Dr Yael Barnett